Andy MacMillan, CEO of Alteryx, discusses the company's AI-centric vision, empowering business users with 'tribal knowledge' to solve complex problems. He highlights Alteryx's evolution towards cloud capabilities and the critical importance of building trust in AI through visibility, understandability, and auditability. MacMillan emphasizes that AI adoption is moving from pilots to production, with a focus on agentics and integrating AI into future job roles.